Active Recombinant Human ACVR1B Protein, GST-tagged
Cat.No. : | ACVR1B-249H |
Product Overview : | Human ACVR1B (NP_004293.1, 150 a.a. - 505 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. |
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Species : | Human |
Source : | Insect Cells |
Tag : | GST |
Protein Length : | 150-505 a.a. |
Description : | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010] |
Form : | Liquid |
Bio-activity : | The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: TopoIIa peptide. ATP: 100 uM. |
Molecular Mass : | 68 kDa |
Purity : | 76 % by SDS-PAGE/CBB staining |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol) |
Gene Name | ACVR1B activin A receptor, type IB [ Homo sapiens ] |
Official Symbol | ACVR1B |
Synonyms | ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB; |
Gene ID | 91 |
mRNA Refseq | NM_004302 |
Protein Refseq | NP_004293 |
MIM | 601300 |
UniProt ID | P36896 |
◆ Recombinant Proteins | ||
ACVR1B-5295H | Recombinant Human Activin A Receptor, Type IB, GST-tagged | +Inquiry |
ACVR1B-1289H | Recombinant Human ACVR1B Protein (N150-I505), His tagged | +Inquiry |
ACVR1B-169H | Recombinant Human ACVR1B Protein, His-tagged | +Inquiry |
ACVR1B-231H | Recombinant Human ACVR1B protein, GST/His-tagged | +Inquiry |
ACVR1B-93R | Recombinant Rhesus ACVR1B protein, hFc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACVR1B-1206RCL | Recombinant Rat ACVR1B cell lysate | +Inquiry |
ACVR1B-2130HCL | Recombinant Human ACVR1B cell lysate | +Inquiry |
ACVR1B-1356CCL | Recombinant Cynomolgus ACVR1B cell lysate | +Inquiry |
Not For Human Consumption!
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