Recombinant Full Length Human small nuclear ribonucleoprotein 70kDa (U1) Protein, His&Avi-tagged

• Cat.No.: SNRNP70-2059H
• Product Overview: Recombinant Full Length Human SNRNP70 Protein with His&Avi-tag was expressed in CHO.

Specification

• Description: Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease.
• Source: CHO
• Species: Human
• Tag: His&Avi
• Protein length: Full Length
• Molecular Mass: 18 kDa
• AA Sequence: MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGYLAPENGYLMEAAPEHHHHHHHHGLNDIFEAQKIEWHE
• Endotoxin: < 1 EU/μg by LAL.
• Purity: > 80 % by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.03 mg/mL by BCA

Gene Information

• Gene Name: SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) [Homo sapiens (human)]
• Official Symbol: SNRNP70
• Synonyms: SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); RNPU1Z, RPU1, small nuclear ribonucleoprotein 70kDa (RNP antigen) , SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; Snp1; U1 70K; U1 snRNP 70 kDa; RPU1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K
• Gene ID: 6625
• mRNA Refseq: NM_003089
• Protein Refseq: NP_003080
• MIM: 180740
• UniProt ID: P08621