Recombinant Human SNRNP70 Protein, His-tagged

Cat.No. : SNRNP70-2711H
Product Overview : Recombinant Human SNRNP70 Protein (Met1-Glu437) with a N-His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Met1-Glu437
Description : Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.3 kDa
Accurate Molecular Mass: 44 kDa
Endotoxin : <1.0 EU per 1µg (determined by the LAL method).
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) [ Homo sapiens (human) ]
Official Symbol SNRNP70
Synonyms SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); RNPU1Z, RPU1, small nuclear ribonucleoprotein 70kDa (RNP antigen), SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; Snp1; U1 70K; U1 snRNP 70 kDa; RPU1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K;
Gene ID 6625
mRNA Refseq NM_003089
Protein Refseq NP_003080
MIM 180740
UniProt ID P08621

Not For Human Consumption!

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