Recombinant Full Length Human RAP1A Protein, His-tagged

• Cat.No.: RAP1A-2584H
• Product Overview: Recombinant Full Length Human RAP1A Protein, His-tagged, expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-184 aa
• Description: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
• Tag: C-His
• Molecular Mass: 22 kDa
• AA Sequence: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLLHHHHHHHH
• Purity: >80% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 °C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.58mg/ml by BCA
• Storage Buffer: Sterile PBS, pH 7.4, 10% Glycerol, 5% Trehalose

Gene Information

• Gene Name: RAP1A RAP1A, member of RAS oncogene family [ Homo sapiens (human) ]
• Official Symbol: RAP1A
• Synonyms: RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21;RAP1A
• Gene ID: 5906
• MIM: 179520
• UniProt ID: P62834