Recombinant Full Length Human PRG4 Protein, Flag tagged

• Cat.No.: PRG4-1574HFL
• Product Overview: Recombinant Full Length Human PRG4 Protein (1-1404 aa) with Flag tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&Non
• Protein Length: 1-1404 aa
• Description: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 152.9 kDa
• Endotoxin: < 1 EU/μg of the protein by LAL
• Purity: >80% by SDS-PAGE
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process
• Storage: Store at -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Stable for at least 1 year from receipt of products under proper storage and handling conditions
• Storage Buffer: 25mM Tris-HCl, 100mM glycine, and 10% glycerol, pH 7.3
• Concentration: 0.05 mg/mL determined by Microplate Bradford Protein Assay method

Gene Information

• Gene Name: PRG4 proteoglycan 4 [ Homo sapiens (human) ]
• Official Symbol: PRG4
• Synonyms: PRG4; proteoglycan 4; CACP, proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome); articular superficial zone protein; bG174L6.2; bG174L6.2 (MSF: megakaryocyte stimulating factor ); camptodactyly; arthropathy; coxa vara; pericarditis syndrome; FLJ32635; HAPO; Jacobs camptodactyly arthropathy pericarditis syndrome; JCAP; lubricin; megakaryocyte stimulating factor; MSF; SZP; superficial zone proteoglycan; megakaryocyte-stimulating factor; CACP
• Gene ID: 10216
• mRNA Refseq: NM_001127708
• Protein Refseq: NP_001121180
• MIM: 604283
• UniProt ID: Q92954