Recombinant Full Length Human MYC, His-tagged

• Cat.No.: MYC-1029H
• Product Overview: Recombinant humanMYC full-length protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by nickel NTA affinity chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-454 a.a.
• Description: c-Myc is a conserved cellular gene. The gene product is a nuclear-bound 62,000 molecular weight phosphoprotein (p62c-myc). The nuclear p62c-myc content increased with DNA synthesis in tumors and mucosa.
• Formulation: 50 μg recombinant protein in Renaturation buffer ( 20 mM Tris-HCl , 150 mM NaCl, 1 mM EDTA, 5 mM Glutathione,0.5 mM GSSH and 10% Glycerol), lyophilized.Reconstitute the contents using sterile water no less than 100 μg/ml.
• Molecular weight: 62 kDa
• Purity: > 90% by SDS PAGE and coomassie blue staining.
• Usage: It can be used for WB, ELISA.
• Storage: Upon receiving, the proteins can be stored at 4°C. After reconstitution,store the working aliquots at -80°C. Avoid repeated freeze and thaw.

Gene Information

• Gene Name: MYC v-myc myelocytomatosis viral oncogene homolog (avian) [ Homo sapiens ]
• Synonyms: MYC; v-myc myelocytomatosis viral oncogene homolog (avian); MRTL; c-Myc; bHLHe39; avian myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor
• Gene ID: 4609
• mRNA Refseq: NM_002467
• Protein Refseq: NP_002458
• MIM: 190080
• UniProt ID: P01106
• Chromosome Location: 8q24
• Pathway: Acute myeloid leukemia; Bladder cancer; Chronic myeloid leukemia; Colorectal cancer; ErbB signaling pathway; Colorectal cancer; Jak-STAT signaling pathway; MAPK signaling pathway; Pathways in cancer; Small cell lung cancer; Small cell lung cancer; Thyroid cancer; Wnt signaling pathway
• Function: protein binding; transcription factor activity