Recombinant Full Length Human HDLBP Protein, C-Flag-tagged

• Cat.No.: HDLBP-1917HFL
• Product Overview: Recombinant Full Length Human HDLBP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 141.3 kDa
• AA Sequence: MSSVAVLTQESFAEHRSGLVPQQIK VATLNSEEESDPPTYKDAFPPLPEK AACLESAQEPAGAWGNKIRP IKASVITQVFHVPLEERKYKDMNQF GEGEQAKICLEIMQRTGAHLELSLA KDQGLSIMVSGKLDAVMKAR KDIVARLQTQASATVAIPKEHHRFV IGKNGEKLQDLELKTATKIQIPRPD DPSNQIKITGTKEGIEKARH EVLLISAEQDKRAVERLEVEKAFHP FIAGPYNRLVGEIMQETGTRINIPP PSVNRTEIVFTGEKEQLAQA VARIKKIYEEKKKKTTTIAVEVKKS QHKYVIGPKGNSLQEILERTGVSVE IPPSDSISETVILRGEPEKL GQALTEVYAKANSFTVSSVAAPSWL HRFIIGKKGQNLAKITQQMPKVHIE FTEGEDKITLEGPTEDVNVA QEQIEGMVKDLINRMDYVEINIDHK FHRHLIGKSGANINRIKDQYKVSVR IPPDSEKSNLIRIEGDPQGV QQAKRELLELASRMENERTKDLIIE QRFHRTIIGQKGERIREIRDKFPEV IINFPDPAQKSDIVQLRGPK NEVEKCTKYMQKMVADLVENSYSIS VPIFKQFHKNIIGKGGANIKKIREE SNTKIDLPAENSNSETIIIT GKRANCEAARSRILSIQKDLANIAE VEVSIPAKLHNSLIGTKGRLIRSIM EECGGVHIHFPVEGSGSDTV VIRGPSSDVEKAKKQLLHLAEEKQT KSFTVDIRAKPEYHKFLIGKGGGKI RKVRDSTGARVIFPAAEDKD QDLITIIGKEDAVREAQKELEALIQ NLDNVVEDSMLVDPKHHRHFVIRRG QVLREIAEEYGGVMVSFPRS GTQSDKVTLKGAKDCVEAAKKRIQE IIEDLEAQVTLECAIPQKFHRSVMG PKGSRIQQITRDFSVQIKFP DREENAVHSTEPVVQENGDEAGEGR EAKDCDPGSPRRCDIIIISGRKEKC EAAKEALEALVPVTIEVEVP FDLHRYVIGQKGSGIRKMMDEFEVN IHVPAPELQSDIIAITGLAANLDRA KAGLLERVKELQAEQEDRAL RSFKLSVTVDPKYHPKIIGRKGAVI TQIRLEHDVNIQFPDKDDGNQPQDQ ITITGYEKNTEAARDAILRI VGELEQMVSEDVPLDHRVHARIIGA RGKAIRKIMDEFKVDIRFPQSGAPD PNCVTVTGLPENVEEAIDHI LNLEEEYLADVVDSEALQVYMKPPA HEEAKAPSRGFVVRDAPWTASSSEK APDMSSSEEFPSFGAQVAPK TLPWGPKR TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: HDLBP high density lipoprotein binding protein [ Homo sapiens (human) ]
• Official Symbol: HDLBP
• Synonyms: HBP; VGL; PRO2900
• Gene ID: 3069
• mRNA Refseq: NM_005336.6
• Protein Refseq: NP_005327.1
• MIM: 142695
• UniProt ID: Q00341

Reviews

07/05/2021

Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.

01/06/2019

Great performance in ELISA.

05/05/2016

Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress

Q&As

How is HDLBP protein used as a biomarker in clinical diagnosis?

Levels of HDLBP protein in blood can serve as a biomarker for assessing the risk of cardiovascular diseases and metabolic disorders.

What diseases are associated with HDLBP dysfunction?

Dysfunctions in HDLBP have been associated with cardiovascular diseases, metabolic disorders, and certain types of cancer.

Can HDLBP protein be used as a therapeutic target?

Research suggests that targeting HDLBP protein may offer potential therapeutic benefits in managing lipid-related disorders and certain types of cancer.

Are there any genetic variations of HDLBP protein associated with disease risk?

Certain genetic variations in the HDLBP gene have been linked to an increased risk of cardiovascular diseases and metabolic disorders.

How can HDLBP protein be measured in clinical settings?

Enzyme-linked immunosorbent assay (ELISA) and western blot analysis are common methods used to measure the levels of HDLBP protein in clinical samples.