Recombinant Human HDLBP protein, His & T7-tagged

• Cat.No.: HDLBP-7856H
• Product Overview: Recombinant Human HDLBP aa. (Pro158~Ala371 (Accession # Q00341)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.5kDa.
• Protein length: Pro158~Ala371
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: HDLBP high density lipoprotein binding protein [ Homo sapiens (human) ]
• Official Symbol: HDLBP
• Synonyms: HDLBP; high density lipoprotein binding protein; HBP; VGL; PRO2900; vigilin; HDL-binding protein
• Gene ID: 3069
• mRNA Refseq: NM_001243900.2
• Protein Refseq: NP_001230829.1
• UniProt ID: Q00341

Reviews

07/05/2021

Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.

01/06/2019

Great performance in ELISA.

05/05/2016

Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress

Q&As

How is HDLBP protein used as a biomarker in clinical diagnosis?

Levels of HDLBP protein in blood can serve as a biomarker for assessing the risk of cardiovascular diseases and metabolic disorders.

What diseases are associated with HDLBP dysfunction?

Dysfunctions in HDLBP have been associated with cardiovascular diseases, metabolic disorders, and certain types of cancer.

Can HDLBP protein be used as a therapeutic target?

Research suggests that targeting HDLBP protein may offer potential therapeutic benefits in managing lipid-related disorders and certain types of cancer.

Are there any genetic variations of HDLBP protein associated with disease risk?

Certain genetic variations in the HDLBP gene have been linked to an increased risk of cardiovascular diseases and metabolic disorders.

How can HDLBP protein be measured in clinical settings?

Enzyme-linked immunosorbent assay (ELISA) and western blot analysis are common methods used to measure the levels of HDLBP protein in clinical samples.