Recombinant Full Length Human DYNC1I2 Protein, GST-tagged

• Cat.No.: DYNC1I2-4144HF
• Product Overview: Human DYNC1I2 full-length ORF ( AAH15038.1, 1 a.a. - 612 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 94.8 kDa
• Protein length: 612 amino acids
• AA Sequence: MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSMGLTPESPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 [ Homo sapiens ]
• Official Symbol: DYNC1I2
• Synonyms: DYNC1I2; dynein, cytoplasmic 1, intermediate chain 2; DNCI2, dynein, cytoplasmic, intermediate polypeptide 2; cytoplasmic dynein 1 intermediate chain 2; DH IC-2; dynein intermediate chain 2, cytosolic; cytoplasmic dynein intermediate chain 2; dynein, cytoplasmic, intermediate polypeptide 2; IC2; DNCI2; MGC9324; FLJ21089; FLJ90842; MGC104199; MGC111094
• Gene ID: 1781
• mRNA Refseq: NM_001378
• Protein Refseq: NP_001369
• MIM: 603331
• UniProt ID: Q13409