DYNC1I2
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Official Full Name
dynein, cytoplasmic 1, intermediate chain 2 -
Overview
Cytoplasmic dynein 1 intermediate chain 2 is a protein that in humans is encoded by the DYNC1I2 gene. -
Synonyms
DYNC1I2;dynein, cytoplasmic 1, intermediate chain 2;DNCI2, dynein, cytoplasmic, intermediate polypeptide 2;cytoplasmic dynein 1 intermediate chain 2;DH IC 2;DNCI2;DNCIC2;Dynein intermediate chain 2, cytosolic;Dynein, cytoplasmic, intermediate polypeptide 2;IC2;DH IC-2;cytoplasmic dynein intermediate chain 2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DYNC1I2-12227H | Recombinant Human DYNC1I2, GST-tagged | E.coli | Human | GST | C-term-309a.a. | |
| DYNC1I2-1359R | Recombinant Rhesus monkey DYNC1I2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| DYNC1I2-1657C | Recombinant Chicken DYNC1I2 | Mammalian Cell | Chicken | His |
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| DYNC1I2-2968H | Recombinant Human DYNC1I2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DYNC1I2-239HCL | Recombinant Human DYNC1I2 lysate | HEK293 | Human | Non |
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| DYNC1I2-1184R | Recombinant Rhesus Macaque DYNC1I2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| DYNC1I2-1184R-B | Recombinant Rhesus Macaque DYNC1I2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| DYNC1I2-4144HF | Recombinant Full Length Human DYNC1I2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 612 amino acids |
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Involved Pathway
DYNC1I2 involved in several pathways and played different roles in them. We selected most pathways DYNC1I2 participated on our site, such as Adaptive Immune System,Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNC1I2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | ASB9,NCKIPSD,BTR06,KIF2C,SIGLEC5,UBE2E3,TRIM6,DUSP3,KIF11,IFIT11 |
| Cell cycle | ORC2L,CDC7,VRK2,CEP63,YWHAH,RAD21A,CDC25C,CDKN2A,ESPL1,ANAPC1 |
| Centrosome maturation | CEP290,NEDD1,CEP78,CLASP1,CEP70,DCTN1,ODF2B,CLASP1A,MAPRE1,OFD1 |
| Cell Cycle, Mitotic | LIN37,ZW10,FGFR1OP,GINS3,NCAPD3,LMNB1,MAPRE1,CKS1B,NINL,SET |
| Adaptive Immune System | KIFAP3,RAPGEF3,RAPGEF4,EGFR,CD200R3,PJA2,FAM49BA,SPSB4,SIGLEC6,PIK3AP1 |
| Assembly of the primary cilium | DYNLL2A,EXOC3,TNPO1,IFT46,OST4,C11orf60,BBS2,TTC26,B9D2,TCTN3 |
| G2/M Transition | CDK11A,CEP135,TUBGCP2,CCP110,CKAP5,LIN52,DCTN1A,NDE1,HAUS2,CEP70 |
| Anchoring of the basal body to the plasma membrane | CDK5RAP2,TUBB4B,CSNK1E,DCTN1,TSGA14,ACTR1A,CCP110,PLK4,CEP135,NEDD1 |
Protein Function
DYNC1I2 has several biochemical functions, for example, microtubule motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNC1I2 itself. We selected most functions DYNC1I2 had, and list some proteins which have the same functions with DYNC1I2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule motor activity | APPBP2,KIF7,KIF9,DNAI2,KIF12,KIF4A,KIF14,KIF2A,KIF1B,KIF2C |
| protein binding | SLC2A4,ATP7B,RQCD1,RTP4,SETD6,CYP4F2,PPP1R12C,RSPH3,PSG5,RBP7 |
Interacting Protein
DYNC1I2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNC1I2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNC1I2.
DYNLRB1;vpr;Dync1i2;DYNLL1;Dynll1;Dync1h1;DYNLT3;pi3p;15-deoxy-delta(12,14;midostaurin;1C
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References
- Cao, JJ; Lin, C; et al. Circovirus Transport Proceeds via Direct Interaction of the Cytoplasmic Dynein IC1 Subunit with the Viral Capsid Protein. JOURNAL OF VIROLOGY 89:2777-2791(2015).
- Ma, C; Yao, Y; et al. Differential Proteomic Analysis of Platelets Suggested Possible Signal Cascades Network in Platelets Treated with Salvianolic Acid B. PLOS ONE 6:-(2011).
