Recombinant Full Length Human CYP2C9 Protein, GST-tagged

Cat.No. : CYP2C9-113HF
Product Overview : Human CYP2C9 full-length ORF ( AAH20754.1, 1 a.a. - 162 a.a.) recombinant protein with GST-tag at N-terminal.
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Species : Human
Source : In Vitro Cell Free System
Tag : GST
Protein Length : 1 a.a. - 162 a.a.
Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Molecular Mass : 43.56 kDa
AA Sequence : MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI SKSLTNLSKV YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF PLAERANRGF GIVFSNGKKW KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR CLVEELRKTK GG
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot; Antibody Production; Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens (human) ]
Official Symbol CYP2C9
Synonyms CYP2C9; CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9; cytochrome P450, family 2, subfamily C, polypeptide 9; cytochrome P450 2C9; cytochrome P-450MP; cytochrome P450 PB-1; microsomal monooxygenase; xenobiotic monooxygenase; flavoprotein-linked monooxygenase; cytochrome P-450 S-mephenytoin 4-hydroxylase; EC 1.14.13.48; EC 1.14.13.49; EC 1.14.13.80
Gene ID 1559
mRNA Refseq NM_000771
Protein Refseq NP_000762
MIM 601130
UniProt ID P11712

Not For Human Consumption!

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