Recombinant Full Length Human CIDEA protein, His & GST-tagged

• Cat.No.: CIDEA-1834H
• Product Overview: Recombinant Human CIDEA aa. (Met1~Gly219 (Accession # O60543)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 57.1kDa
• Protein length: Met1~Gly219
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.2

Gene Information

• Gene Name: CIDEA cell death-inducing DFFA-like effector a [ Homo sapiens (human) ]
• Official Symbol: CIDEA
• Synonyms: CIDEA; cell death-inducing DFFA-like effector a; CIDE-A; cell death activator CIDE-A
• Gene ID: 1149
• mRNA Refseq: NM_001279.3
• Protein Refseq: NP_001270.1
• UniProt ID: O60543