CIDEA

  • Official Full Name

    cell death-inducing DFFA-like effector a

  • Overview

    This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

  • Synonyms

    CIDEA;cell death-inducing DFFA-like effector a;cell death activator CIDE-A;CIDE A;CIDE-A

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • E.coli
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Fc&Avi
  • His&GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
CIDEA-1361H Recombinant Human CIDEA Protein, GST-tagged Wheat Germ Human GST
CIDEA-3471M Recombinant Mouse CIDEA Protein Mammalian Cell Mouse His
CIDEA-4130C Recombinant Chicken CIDEA Mammalian Cell Chicken His
CIDEA-358HCL Recombinant Human CIDEA cell lysate Human Non
CIDEA-1690M Recombinant Mouse CIDEA Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CIDEA-1690M-B Recombinant Mouse CIDEA Protein Pre-coupled Magnetic Beads HEK293 Mouse
CIDEA-1834H Recombinant Full Length Human CIDEA protein, His & GST-tagged E.coli Human His&GST Full L. Met1~Gly219
CIDEA-1848HF Recombinant Full Length Human CIDEA Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 253 amino acids
Cidea-789M Recombinant Mouse Cidea Protein, His-tagged E.coli Mouse His Met1-Met217

    Involved Pathway

    CIDEA involved in several pathways and played different roles in them. We selected most pathways CIDEA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CIDEA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    CIDEA has several biochemical functions, for example, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CIDEA itself. We selected most functions CIDEA had, and list some proteins which have the same functions with CIDEA. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity FGFR1,GSTM4,Pdgfa&Pdgfb,NUDT21,IKBKB,CSF1R,SETMAR,UGT1A1,Defa-rs7,SNX6

    Interacting Protein

    CIDEA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CIDEA here. Most of them are supplied by our site. Hope this information will be useful for your research of CIDEA.

    Dlg4;NR1H2;ZBTB16

    Resources

    Research Area

    Apoptosis Adaptor Proteins
    Adaptor Proteins
    Adaptor Proteins in the Akt Pathway
    Adipogenesis Markers

    References

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