Recombinant Full Length Human ACVR1C Protein, Flag Tagged

• Cat.No.: ACVR1C-1019
• Product Overview: Purified recombinant protein of Homo sapiens activin A receptor, type IC (ACVR1C), transcript variant 4 with C-Flag tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 1-493aa
• Description: ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
• Tag: C-Flag
• Molecular Mass: 37.3 kDa
• AA Sequence: MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKATRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Concentration: > 0.05 μg/μL as determined by microplate BCA method

Gene Information

• Gene Name: ACVR1C activin A receptor type 1C [ Homo sapiens (human) ]
• Official Symbol: ACVR1C
• Synonyms: ACVR1C; activin A receptor type 1C; ALK7; ACVRLK7; activin receptor type-1C; ACTR-IC; ALK-7; activin A receptor, type IC; activin receptor type IC; activin receptor-like kinase 7; EC 2.7.11.30
• Gene ID: 130399
• mRNA Refseq: NM_001111033
• Protein Refseq: NP_001104503
• MIM: 608981
• UniProt ID: Q8NER5