Recombinant Human ACVR1C, GST-tagged
Cat.No. : | ACVR1C-9356H |
Product Overview : | Recombinant Human ACVR1C protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Availability | March 16, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | C-term-355a.a. |
Description : | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | ACVR1C activin A receptor, type IC [ Homo sapiens ] |
Official Symbol | ACVR1C |
Synonyms | ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7; |
Gene ID | 130399 |
mRNA Refseq | NM_001111031 |
Protein Refseq | NP_001104501 |
MIM | 608981 |
UniProt ID | Q8NER5 |
Chromosome Location | 2q24.2 |
Pathway | Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem; |
Function | ATP binding; activin receptor activity, type I; metal ion binding; nucleotide binding; receptor activity; transforming growth factor beta-activated receptor activity; |
◆ Recombinant Proteins | ||
ACVR1C-256H | Recombinant Human ACVR1C protein, His-tagged | +Inquiry |
ACVR1C-8816C | Recombinant Cynomolgus ACVR1C, Fc tagged | +Inquiry |
ACVR1C-2311R | Recombinant Rhesus ACVR1C protein, hFc-tagged | +Inquiry |
ACVR1C-6996H | Recombinant Human ALK7, GST-tagged | +Inquiry |
ACVR1C-252H | Recombinant Human ACVR1C Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACVR1C-1277CCL | Recombinant Cynomolgus ACVR1C cell lysate | +Inquiry |
Not For Human Consumption!
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