Recombinant Cynomolgus FCGRT & B2M protein, His-Avi-tagged

• Cat.No.: FCGRT & B2M-103C
• Product Overview: Recombinant Cynomolgus FcRn Protein is expressed from mammalian with a His tag and Avi Tag at the C-terminal.. It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M).

Specification

• Description: The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
• Source: HEK293
• Species: Cynomolgus
• Tag: His&Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 48-50KD based on Bis-Tris PAGE result.
• Protein length: It contains Met1-Ser297(FCGRT) & Met1-Met119(B2M) .
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: FCGRT Fc fragment of IgG receptor and transporter [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: FCGRT; B2M
• Synonyms: FcRn alpha chain; alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig
• Gene ID: 102128913
• mRNA Refseq: NM_001284551.1
• Protein Refseq: NP_001271480.1
• UniProt ID: Q8SPV9