Recombinant Chicken SIRT2

• Cat.No.: SIRT2-2178C
• Product Overview: Recombinant Chicken SIRT2 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Chicken
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: SIRT2 sirtuin 2 [ Gallus gallus (chicken) ]
• Official Symbol: SIRT2
• Gene ID: 548628
• Protein Refseq: NP_001017414
• UniProt ID: Q5ZID4

Reviews

04/15/2021

Efficient and knowledgeable customer service—made our purchase straightforward.

11/02/2020

This recombined protein is our go-to for dependable and accurate results.

08/30/2018

Punctual delivery is crucial, and this product arrived right on time.

Q&As

How does SIRT2 participate in the regulation of cellular stress responses?

SIRT2 is involved in stress response pathways, deacetylating and modulating the activity of stress-responsive proteins, contributing to cellular adaptation to various stress conditions.

How does SIRT2 contribute to the regulation of cellular metabolism?

SIRT2 influences cellular metabolism by deacetylating enzymes involved in glycolysis, fatty acid metabolism, and mitochondrial function, impacting overall energy homeostasis.

Explain the molecular mechanisms underlying SIRT2-mediated deacetylation of target proteins.

SIRT2 uses NAD+ as a cofactor to remove acetyl groups from lysine residues, a process that links cellular metabolic state to protein acetylation and deacetylation.

Discuss the role of SIRT2 in the regulation of cell cycle progression.

SIRT2 influences cell cycle progression by deacetylating key regulators, such as cyclin-dependent kinases (CDKs) and checkpoint proteins, impacting cell cycle checkpoints and progression.

Discuss the role of SIRT2 in neurodegenerative diseases and its potential as a therapeutic target.

SIRT2 has been implicated in neurodegenerative diseases, and modulating its activity is explored as a potential therapeutic strategy for conditions such as Parkinson's disease.