Native Human Prostate Specific Antigen

• Cat.No.: KLK3-8247H
• Product Overview: Human Prostate Specific Antigen was purified from Human Seminal Fluid.

Specification

• Species: Human
• Source: Human Seminal Fluid
• Tag: Non
• Description: Prostate-specific antigen (PSA) also known as gamma-seminoprotein or kallikrein-3 is a glycoprotein that in humans is encoded by the KLK3 gene. PSA is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. PSA is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm.
• Form: Phosphate buffer and sodium chloride solution
• Molecular Mass: 34,000 monomeric protein
• Purity: >98% by SDS-PAGE
• Storage: 2-8 °C
• Concentration: Typically >2.0 mg/mL

Gene Information

• Gene Name: KLK3 kallikrein-related peptidase 3 [ Homo sapiens ]
• Official Symbol: KLK3
• Synonyms: KLK3; kallikrein-related peptidase 3; APS, kallikrein 3, (prostate specific antigen); prostate-specific antigen; PSA; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen; APS; hK3; KLK2A1
• Gene ID: 354
• mRNA Refseq: NM_001030047
• Protein Refseq: NP_001025218
• MIM: 176820
• UniProt ID: P07288
• Chromosome Location: 19q13.41
• Pathway: Coregulation of Androgen receptor activity, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem
• Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity