Native Human GFAP protein

• Cat.No.: GFAP-526H
• Product Overview: Native Human GFAP protein purified from Human Brain.

Specification

• Species: Human
• Source: Human Brain
• Tag: Non
• Description: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Form: Lyophilized from urea, sodium phosphate, and sodium bicarbonate.
• Molecular Mass: 43,000-49,000
• Purity: ≥90% by SDS-PAGE
• Notes: Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
• Stability: Following reconstitution, aliquot and freeze (-20 centigrade). Stock solutions are stable for up to 3 months at -20 centigrade.
• Storage: Storage at -20 centigrade.
• Reconstitution: dH2O (1 mg/ml)

Gene Information

• Gene Name: GFAP glial fibrillary acidic protein [ Homo sapiens ]
• Official Symbol: GFAP
• Synonyms: GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein; FLJ42474
• Gene ID: 2670
• mRNA Refseq: NM_001131019
• Protein Refseq: NP_001124491
• MIM: 137780
• UniProt ID: P14136
• Chromosome Location: 17q21
• Pathway: Nuclear signaling by ERBB4, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB4, organism-specific biosystem
• Function: integrin binding; structural constituent of cytoskeleton