Native Human Creatine Kinase MM (CK-MM)

• Cat.No.: CKMM-382H
• Product Overview: Native Human Creatine Kinase MM (CK-MM) was purified from Human Heart.

Specification

• Species: Human
• Source: Human Heart
• Tag: Non
• Description: Human Creatine phosphokinase (CK)CPK isoenzymes are performed when the total human CPK level is elevated. Human CK(CPK)Isoenzyme testing can help differentiate the source of the damaged tissue. Human (CPK)CK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Human (CKMM)CK-MM, Human (CKBB)CK-BB isoenzyme and Human (CKMB)CK-MB isoenzyme exist.
• Form: Lyophilized from 40 mM Tris-Cl, 1 mM EDTA, 10 mM NaCl
• Purity: >96% (SDS-PAGE)
• Unit Definition: One unit will transfer one mmole of phosphate from Creatine Phosphate to ATP per minute at 37C. Measured at 340 nm as one equimolar amount of NADH produced by a coupled reaction.
• Storage: Store at -20 °C
• Concentration: Typically >0.25 mg/mL

Gene Information

• Gene Name: CKM creatine kinase, muscle [ Homo sapiens ]
• Official Symbol: CKM
• Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK
• Gene ID: 1158
• mRNA Refseq: NM_001824
• Protein Refseq: NP_001815
• MIM: 123310
• UniProt ID: P06732
• Chromosome Location: 19q13.32
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Creatine pathway, organism-specific biosystem; Creatine pathway, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: ATP binding; creatine kinase activity; nucleotide binding