Native Human Apolipoprotein A-II

• Cat.No.: APOA2-5302H
• Product Overview: Native human APOA2was expressed in human plasma.Itsmolecular weight is 17380 Dalton.

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: Human APOA2 is one of a family of evolutionarilyrelated proteins which play a crucial role in lipid transport and metabolism.The serum levels of Human APOA2 have been shown to be inversely correlated tothe incidence of coronary heart disease and its expression to be limited tothe liver and intestine. APOA2 is the second most abundant protein of thehigh density lipoprotein particles. The protein is found in plasma as amonomer, homodimer, or heterodimer with apolipoprotein D. Defects in thisgene may result in APOA2 deficiency or hypercholesterolemia.
• Form: Liquid in 75 mM PBSpH 7.2 + 75 mM NaCl.
• Concentration: Typically 1 mg/mL
• MolecularWeight: 17.38 kDa
• Purity: > 99% bySDS-PAGE
• Storage: Store at -20°C.
• OfficialSymbol: APOA2

Gene Information

• Gene Name: APOA2 apolipoprotein A-II [ Homosapiens ]
• Synonyms: APOA2;apolipoprotein A-II; apoAII; Apo-AII; ApoA-II; Hdl-1; Alp-2; Apoa-2; ApoAII;APOAII; Apoa2; apolipoprotein A2; OTTHUMP00000032244; Apolipoprotein A-II;Apolipoprotein A2
• Gene ID: 336
• mRNA Refseq: NM_001643
• Protein Refseq: NP_001634
• MIM: 107670
• UniProt ID: P02652
• Chromosome Location: 1q21-q23
• Pathway: Chylomicron-mediatedlipid transport; Fatty acid, triacylglycerol, and ketone body metabolism;Lipid digestion, mobilization, and transport; Lipoprotein metabolism;Metabolism of lipids and lipoproteins; PPAR signaling pathway; PPAR signalingpathway; Regulation of Lipid Metabolism by Peroxisome proliferator-activatedreceptor alpha (PPARalpha); Statin Pathway
• Function: cholesterol binding;contributes to cholesterol transporter activity; high-density lipoproteinparticle binding; high-density lipoprotein particle receptor binding; lipaseinhibitor activity; lipid binding; lipid transporter activity;phosphatidylcholine binding; phosphatidylcholine-sterol O-acyltransferaseactivator activity; phospholipid binding; protein binding; proteinheterodimerization activity; protein homodimerization activity