APOA2
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Official Full Name
apolipoprotein A-II -
Overview
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008] -
Synonyms
APOA2;apolipoprotein A-II;apoAII;Apo-AII;ApoA-II;apolipoprotein A2
Recombinant Proteins
- Human
- Mouse
- Pig
- Rat
- Zebrafish
- Dog
- E.coli
- Mammalian Cell
- Wheat Germ
- E.Coli or Yeast
- Human Cell
- HEK293
- Mammalian cells
- In Vitro Cell Free System
- CHO
- Human Plasma
- Human plasma
- GST
- His
- His&GST
- Non
- SUMO
- His&SUMO
- His&Fc&Avi
- Fc
Involved Pathway
APOA2 involved in several pathways and played different roles in them. We selected most pathways APOA2 participated on our site, such as PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | PPARG,FABP2,FADS2,PPARAB,PPARD,AQP7,CYP4A10,SLC27A5,PPARDB,FABP1A |
Protein Function
APOA2 has several biochemical functions, for example, apolipoprotein receptor binding,cholesterol binding,contributes_to cholesterol transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOA2 itself. We selected most functions APOA2 had, and list some proteins which have the same functions with APOA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipase inhibitor activity | APOC1,FAF2,APOC3,APOC2,APOA1 |
| high-density lipoprotein particle receptor binding | APOA1,APOC3 |
| protein binding | MTTP,ROR1,NAE1,MPLKIP,IFIT2,KCNA3,SMURF2,KAT2B,THEMIS,TRAPPC6B |
| cholesterol binding | APOA4B.2,APOA1,OSBP2,APOA5,ANXA6,CYP11A1,ABCG1,SOAT1,OSBPL2,OSBPL5 |
| protein homodimerization activity | EXT1,TGFB1,PLOD1,FAM109A,JUP,UGT1A4,WHRN,HLCS,FLT3,SLC16A1 |
| phosphatidylcholine binding | APOC1,APOA5,CHMP3,APOA1,CHMP2A,APOA4,SERPINA5,VPS24,RPE65,APOA4B.1 |
| high-density lipoprotein particle binding | APOA1A,APOL2,GPIHBP1,APOA1 |
| contributes_to cholesterol transporter activity | APOA1,ABCG8,ABCG5,SFRP5 |
| phosphatidylcholine-sterol O-acyltransferase activator activity | APOA4A,APOA5,APOEA,APOE,APOA1A,APOA4,APOA1,APOEB,APOA4B.1,APOA4B.2 |
Interacting Protein
APOA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOA2.
CATSPER1;CREB3;p27958-pro_0000037566;d-mannose;APOE;APOC2;ALB;APOB
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References
- Chen, HC; Chen, YT; et al. A sensitive and selective magnetic graphene composite-modified polycrystalline-silicon nanowire field-effect transistor for bladder cancer diagnosis. BIOSENSORS & BIOELECTRONICS 66:198-207(2015).
- Chen, CL; Lin, TS; et al. Identification of potential bladder cancer markers in urine by abundant-protein depletion coupled with quantitative proteomics. JOURNAL OF PROTEOMICS 85:28-43(2013).
