Native Bovine Pancreatic Trypsin Inhibitor

Cat. No. :	PTI-1900B
Description :	PTI is a natural proteinase inhibitorpolypeptide consisting of fifty-eight amino acids arranged in a single polypeptidechain, cross-linked by three disulfide bridges and having a MW of 6.512 kDa.
Source :	Bovine lung
Species :	Bovine
Form :	Aprotinin (1 mg/ml)was lyophilized with no additives.
Purity :	Greater than 98.0%as determined by: Analysis by RP-HPLC, anion-exchange FPLC, and analysis byreducing and non-reducing SDS-PAGE Silver Stained gel.
Endotoxin :	Less than 0.1 ng/ug(1 EU/ug) of PTI.
Biological activity :	PTI activitywas found to be 6 x 10⁶ IU/mg.
Storage :	LyophilizedAprotinin although stable at room temperature for 3 weeks, should be storeddesiccated below -18°C. Upon reconstitution Aprotinin should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it isrecommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze-thawcycles.
OfficialSymbol :	PTI
Tag :	Non

Gene Name	PTI pancreatic trypsininhibitor [ Bos taurus ]
Synonyms	PTI; pancreatictrypsin inhibitor; BPI; BPTI; pancreatic trypsin inhibitor; aprotinin; basicprotease inhibitor
Gene ID	404172
mRNA Refseq	NM_001001554
Protein Refseq	NP_001001554
UniProt ID	P00974
Chromosome Location	13
Pathway	Axon guidance; Developmental Biology;Glypican 1 network; NCAM signaling for neurite out-growth; NCAM1interactions; Prion diseases
Function	peptidase inhibitor activity; potassiumchannel inhibitor activity; serine-type endopeptidase inhibitor activity