Recombinant Human NTF2-Like Export Factor 1, His-tagged

• Cat.No.: NXT1-3523H
• Product Overview: Recombinant human NXT1 protein, fused to His-tag at N-terminus, was expressed in E.coliand purified by using conventional chromatography (1-140aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. This protienheterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl
• Molecular Weight: 18.0 kDa (160aa) confirmed by MALDI-TOF
• Purity: >85% by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by BCAassay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASVDFKTYV DQACRAAEEF VNVYYTTMDK RRRLLSRLYM GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT VLVVICGSVK FEGNKQRDFN QNFILTAQAS PSNTVWKIAS DCFRFQDWAS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: NXT1 NTF2-like export factor 1 [ Homo sapiens ]
• Synonyms: NXT1; NTF2-like export factor 1; P15; MTR2; protein p15; NTX2-like export factor1; NUTF-like export factor 1; NTF2-related export protein 1
• Gene ID: 29107
• mRNA Refseq: NM_013248
• Protein Refseq: NP_037380
• MIM: 605811
• UniProt ID: Q9UKK6
• Chromosome Location: 20p12-p11.2
• Function: Ran GTPase binding; protein binding