Recombinant Human NTF2-like Export Factor 1, T7-tagged

• Cat.No.: NXT1-2951H
• Product Overview: Recombinant Human NXT1 was produced inE.coliwith a T7 tag at N-terminus. MW = 15847 Da (1-140 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-140 a.a.
• Description: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: NXT1 NTF2-like export factor 1 [ Homo sapiens ]
• Synonyms: NXT1; NTF2-like export factor 1; P15; MTR2; NTF2-related export protein 1; protein p15; NTX2-like export factor1; NUTF-like export factor 1
• Gene ID: 29107
• mRNA Refseq: NM_013248
• Protein Refseq: NP_037380
• MIM: 605811
• UniProt ID: Q9UKK6
• Chromosome Location: 20p12-p11.2
• Function: Ran GTPase binding; protein binding