Recombinant Human NXT1, T7 -tagged

• Cat.No.: NXT1-28306TH
• Product Overview: Recombinant full length protein (Human) with T7 tag at N terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Description: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
• Conjugation: T7
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Contains 1 NTF2 domain.
• Full Length: Full L.

Gene Information

• Gene Name: NXT1 NTF2-like export factor 1 [ Homo sapiens ]
• Official Symbol: NXT1
• Synonyms: NXT1; NTF2-like export factor 1; NTX2 like export factor1; NTF2-related export protein 1; MTR2; P15
• Gene ID: 29107
• mRNA Refseq: NM_013248
• Protein Refseq: NP_037380
• MIM: 605811
• Uniprot ID: Q9UKK6
• Chromosome Location: 20p12-p11.2
• Pathway: Exon junction complex (EJC), organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem
• Function: Ran GTPase binding; protein binding