Active Recombinant Mouse Sema4a, HIgG1 Fc-tagged

• Cat.No.: Sema4a-4001M
• Product Overview: The extracellular domain of mouse Semaphorin-4A(NP_038686.3) (Met1-Gln676) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to cause collapse of chick embryonic dorsal root ganglia (DRG) neuron growth cones.
• Molecular Mass: 101 KDa
• AA Sequence: Met1-Gln676
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: ≥98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A [ Mus musculus ]
• Official Symbol: Sema4a
• Synonyms: SEMA4A; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; semaphorin-4A; sema B; semaphorin-B; semaphorin 4A; SemB; Semab; AI132332
• Gene ID: 20351
• mRNA Refseq: NM_001163489
• Protein Refseq: NP_001156961
• Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Other semaphorin interactions, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem
• Function: receptor activity