Active Recombinant Mouse Lrp6 Protein, His-tagged

• Cat.No.: Lrp6-1051M
• Product Overview: Recombinant Mouse Lrp6 (Accession # O88572) Ala20-Pro1368, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Ala20
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.rmLRP-6 binds rhDkk-1, biotin with an apparent KD < 15 nM.Biotinylated rmWnt-3a immobilized on a streptavidin-coated plate at 1 µg/mL can bind rmLRP-6 with a linear range of 0.2 - 10 µg/mL.
• Molecular Mass: Recombinant Mouse Lrp6, His-tagged has a calculated MW of 152.6 kDa. In SDS-PAGE migrates as 170 kDa, reducing conditions.
• Protein length: Ala20-Pro1368
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Lrp6 low density lipoprotein receptor-related protein 6 [ Mus musculus ]
• Official Symbol: Lrp6
• Synonyms: LRP6; low density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; crooked; low density lipoprotein-related protein 6; Cd; Gw; C030016K15Rik
• Gene ID: 16974
• mRNA Refseq: NM_008514
• Protein Refseq: NP_032540