Active Recombinant Mouse IGF2 Protein

• Cat.No.: IGF2-123M
• Product Overview: Recombinant Mouse IGF2 Protein without tag was expressed in E. coli.

Specification

• Description: Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.
• Source: E. coli
• Species: Mouse
• Bio-activity: FDC-P1 cell proliferation, ED50≤50 ng/mL
• Molecular Mass: Monomer, 7.4 kDa (with 67 amino acids)
• AA Sequence: AYGPGETLCGGELVDTLQFVCSDRG FYFSRPSSRANRRSRGIVEECCFRS CDLALLETYCATPAKSE
• Endotoxin: ≤1 EUs/μg, Kinetic LAL (50% confidence)
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
• Reconstitution: Sterile water at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: Igf2 insulin-like growth factor 2 [ Mus musculus (house mouse) ]
• Official Symbol: IGF2
• Synonyms: IGF2; insulin-like growth factor 2; insulin-like growth factor II; multiplication-stimulating polypeptide; Mpr; M6pr; Peg2; Igf-2; Igf-II; AL033362
• Gene ID: 16002
• mRNA Refseq: NM_001122736
• Protein Refseq: NP_001116208
• UniProt ID: P09535

Reviews

01/24/2023

The IGF2 protein is an exceptional choice that meets the highest standards of quality, making it perfectly suited for your experimental needs.

01/26/2019

The IGF2 protein is of the highest quality and perfectly suited for your experimental requirements.

01/20/2019

In addition to its exceptional quality, the IGF2 protein is backed by excellent technical support offered by the manufacturer.

Q&As

Can IGF2 be used as a predictive marker for certain diseases?

Yes, IGF2 levels may serve as predictive markers for certain diseases. Monitoring its expression could help identify individuals at risk or track disease progression.

How can IGF2 be targeted for therapeutic interventions?

Researchers are exploring various approaches, including drug development, to modulate IGF2 levels for therapeutic purposes. This may involve targeting its receptors or modifying its expression.

How does IGF2 relate to aging and age-related diseases?

IGF2 has been linked to the aging process and age-related diseases. Exploring its role may provide insights into slowing down aging or managing age-related conditions.

Are there therapeutic applications of IGF2 in regenerative medicine?

Research is exploring the potential use of IGF2 in regenerative medicine due to its role in cell growth and tissue repair. It may offer new avenues for tissue regeneration.

Are there clinical trials exploring IGF2 as a therapeutic target?

Yes, there are ongoing clinical trials investigating the use of IGF2 in various conditions. These trials aim to assess its safety and efficacy in a clinical setting.