Active Recombinant Mouse Erythropoietin Receptor

Cat. No. :	Epor-464M
Description :	Erythropoietin (Epo)is a 34 kDa glycoprotein hormone in the type I cytokine family and is relatedto thrombopoietin. Its three N glycosylation sites, four alpha helices, and NtoCterminal disulfide bond are conserved across species. Glycosylation of Epo isrequired for biological activities in vivo. Mature mouse Epo shares 95% aminoacid sequence identity with rat Epo and 73%-82% with bovine, canine, equine, feline,human, ovine, and porcine EPO.
Source :	Mammalian cells
Form :	Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein.
N-terminalSequence :	Ala27
Molecular Weight :	18.6 kDa
Activity :	Measuredin a cell proliferation assay using TF1 human erythroleukemic cells. Kitamura,T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effectis typically 0.4-2 ng/mL.
Endotoxin Level :	<1.0 EUper 1 μg of the protein by the LAL method.
Purity :	>90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution :	Reconstituteat 10 μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage :	Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution.
Tag :	Non
Protein length :	27-192 a.a.

Gene Name	Epor erythropoietinreceptor [ Mus musculus ]
Official Symbol	Epor
Synonyms	Epor; erythropoietinreceptor; EPO-R
Gene ID	13857
mRNA Refseq	NM_010149
Protein Refseq	NP_034279
UniProt ID	P14753
Chromosome Location	9 A3; 9 5.0 cM
Pathway	Cytokine-cytokine receptorinteraction; EPO Receptor Signaling; Hematopoietic cell lineage; Jak-STAT signalingpathway; Kit Receptor Signaling Pathway
Function	cytokine receptor activity;erythropoietin receptor activity; identical protein binding; protein binding;receptor activity; transmembrane signaling receptor activity