Active Recombinant Mouse Eno2 protein, His-tagged

Description :	Eno2, also known as Gamma enolase isoform1, is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release Eno2 into the blood. Eno2 is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma.
Source :	E. coli
Species :	Mouse
Tag :	His
Form :	Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol
Bio-activity :	Specific activity is > 10,000 pmol/min/ug, and was obtained by measuring the decrease of NAD in absorbance at 340nm resulting from NADH at pH 6.5 at 37°C.
Molecular Mass :	49.7kDa (457aa) confirmed by MALDI-TOF
AA Sequence :	MGSSHHHHHH SSGLVPRGSH MGSMSIEKIW AREILDSRGN PTVEVDLYTA KGLFRAAVPS GASTGIYEAL ELRDGDKQRY LGKGVLKAVD HINSRIAPAL ISSGISVVEQ EKLDNLMLEL DGTENKSKFG ANAILGVSLA VCKAGAAERD LPLYRHIAQL AGNSDLILPV PAFNVINGGS HAGNKLAMQE FMILPVGAES FRDAMRLGAE VYHTLKGVIK DKYGKDATNV GDEGGFAPNI LENSEALELV KEAIDKAGYT EKMVIGMDVA ASEFYRDGKY DLDFKSPADP SRYITGDQLG ALYQDFVRNY PVVSIEDPFD QDDWAAWSKF TANVGIQIVG DDLTVTNPKR IERAVEEKAC NCLLLKVNQI GSVTEAIQAC KLAQENGWGV MVSHRSGETE DTFIADLVVG LCTGQIKTGA PCRSERLAKY NQLMRIEEEL GDEARFAGHN FRNPSVL
Purity :	> 95% by SDS - PAGE
Storage :	Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration :	1mg/ml (determined by Absorbance at 280nm)
Protein length :	1-434 a.a.

Gene Name	Eno2 enolase 2, gamma neuronal [ Mus musculus ]
Official Symbol	Eno2
Synonyms	ENO2; enolase 2, gamma neuronal; gamma-enolase; neural enolase; neuron-specific enolase; 2-phospho-D-glycerate hydro-lyase; NSE; Eno-2; AI837106; D6Ertd375e;
Gene ID	13807
mRNA Refseq	NM_013509
Protein Refseq	NP_038537
UniProt ID	P17183
Chromosome Location	6 F2; 6 59.17 cM
Pathway	Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem;
Function	lyase activity; magnesium ion binding; metal ion binding; phosphopyruvate hydratase activity; protein heterodimerization activity; protein homodimerization activity;