Active Recombinant Mouse CSK Protein, GST & His-tagged

• Cat.No.: CSK-925M
• Product Overview: Recombinant mouse CSK (P41241?) (Met 1-Leu 450) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: GST&His
• Protein Length: 1-450 a.a.
• Predicted N Terminal: Met
• Form: Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% glycerol.
• Bio-activity: The specific activity was determined to be 70 nmol/min/mg using Poly(Glu,Tyr) 4:1 as substrate.
• Molecular Mass: The secreted recombinant mouse CSK/GST chimera consists of 687 amino acids and has a calculated molecular mass of 78.5 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >85 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Csk c-src tyrosine kinase [ Mus musculus ]
• Official Symbol: CSK
• Synonyms: CSK; c-src tyrosine kinase; tyrosine-protein kinase CSK; p50CSK; C-Src kinase; protein-tyrosine kinase MPK-2; AW212630
• Gene ID: 12988
• mRNA Refseq: NM_007783
• Protein Refseq: NP_031809
• Pathway: Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-spe
• Function: ATP binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein binding; protein kinase activity; protein phosphatase binding; protein tyrosine kinase activity; protein tyrosin