Native Human CSK

• Cat.No.: CSK-27872TH
• Product Overview: Full length human CSK with N-terminal proprietary tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Non
• Description: C-src tyrosine kinase, also known as CSK, is a human protein and gene. It includes an SH2 domain, an SH3 domain, and a tyrosine kinase domain.
• Tissue specificity: Expressed in lung and macrophages.
• Biological activity: Specific Activity : 100 U/mg. One unit defined as the amount of enzyme that will transfer 1nmol phosphate to Tyr substrate per minute at pH 7.4 and 30deg.C. Assay buffer : 50mM HEPES pH 7.4, 3mM MgCl2, 3mM MnCl2, 1mM DTT, 3um Na-orthovanadate, 0.1M ATP, 3
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, 10mM reduced Glutathione, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.
• Full Length: Full L.

Gene Information

• Gene Name: CSK c-src tyrosine kinase [ Homo sapiens ]
• Official Symbol: CSK
• Synonyms: CSK; c-src tyrosine kinase; tyrosine-protein kinase CSK
• Gene ID: 1445
• mRNA Refseq: NM_001127190
• Protein Refseq: NP_001120662
• MIM: 124095
• Uniprot ID: P41240
• Chromosome Location: 15q24.1
• Pathway: Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem
• Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein C-terminus binding