Active Recombinant Human TNFRSF11B
Cat.No. : | TNFRSF11B-210H |
Product Overview : | Recombinant Human TNFRSF11B (Accession # AAB53709) Met1-Leu401 was produced in Chinese Hamster Ovary cell line, CHO-derived. |
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Species : | Human |
Source : | CHO |
Tag : | Non |
ProteinLength : | 1-401 a.a. |
Predicted N Terminal : | Glu22 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein. |
Bio-activity : | Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL.The ED50 for this effect is typically 2 -10 ng/mL in the presence of 20 ng/mL Recombinant Human TRAIL/TNFSF10. |
Molecular Mass : | Recombinant Human TNFRSF11B has a calculated MW of 43.6 kDa (monomer). In SDS-PAGE migrates as 54-64 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 100 µg/mL in PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name | TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ] |
Official Symbol | TNFRSF11B |
Synonyms | TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG, osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; OCIF; TR1; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG; MGC29565; |
Gene ID | 4982 |
mRNA Refseq | NM_002546 |
Protein Refseq | NP_002537 |
MIM | 602643 |
UniProt ID | O00300 |
Chromosome Location | 8q24 |
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Not For Human Consumption!
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