Active Recombinant Human SEMA6D Protein, Fc Chimera

• Cat.No.: SEMA6D-841H
• Product Overview: Recombinant Human SEMA6D (Accession # NP_705871), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: Ser22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Human Semaphorin 6D Fc Chimera is coated at 6 µg/mL, Recombinant Mouse Plexin A1 binds with an apparent KD < 50 nM.
• Molecular Mass: Recombinant Human SEMA6D, Fc Chimera has a calculated MW of 98.6 kDa (monomer). In SDS-PAGE migrates as 110-120 kDa (full length) & 88-97 kDa (Fc was cleaved off, 30-35%).
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D [ Homo sapiens ]
• Official Symbol: SEMA6D
• Synonyms: SEMA6D; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; semaphorin-6D; FLJ11598; KIAA1479
• Gene ID: 80031
• mRNA Refseq: NM_001198999
• Protein Refseq: NP_001185928
• MIM: 609295
• UniProt ID: Q8NFY4
• Chromosome Location: 15q21.1