Active Recombinant Human LIPE, His-tagged

• Cat.No.: LIPE-8392H
• Product Overview: Recombinant N-terminal Hexahistadine-tagged protein, expressed in Sf21 insect cells using a baculovirus expression system.

Specification

• Description: The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.
• Source: Sf21 insect cells
• Species: Human
• Tag: His
• Form: A solution in 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol.
• Bio-activity: 3.3U/ml; 15nmols/min/ mg; 0.22mg/ml
• Molecular Mass: 118.3 kDa
• Purity: ≥80%
• Stability: ≥6 months at 80°C; avoid freeze/thaw cycles by aliquoting protein.
• Storage: -80°C

Gene Information

• Gene Name: LIPE lipase, hormone-sensitive [ Homo sapiens (human) ]
• Official Symbol: LIPE
• Synonyms: LIPE; HSL; LHS; lipase, hormone-sensitive; hormone-sensitive lipase; hormone-sensitive lipase testicular isoform; NP_005348.2; EC 3.1.1.79
• Gene ID: 3991
• mRNA Refseq: NM_005357
• Protein Refseq: NP_005348
• MIM: 151750
• UniProt ID: Q05469
• Chromosome Location: 19q13.2
• Pathway: AMPK signaling; Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis; Triacylglyceride Synthesis
• Function: hormone-sensitive lipase activity; protein binding; protein kinase binding