Active Recombinant Human KIR2DL5A Protein, Fc Chimera

• Cat.No.: KIR2DL5A-728H
• Product Overview: Recombinant Human KIR2DL5A (Accession # NP_065396), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: His22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind HLA on MDA-MB-231 human breast cancer cells.The ED50 for this effect is typically 0.9 - 3.6 µg/mL. Optimal dilutions should be determined by each laboratory for each application.
• Molecular Mass: Recombinant Human KIR2DL5A, Fc Chimera has a calculated MW of 50.1 kDa (monomer). In SDS-PAGE migrates as 66 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [ Homo sapiens ]
• Official Symbol: KIR2DL5A
• Synonyms: KIR2DL5A; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A; CD158F; KIR2DL5; KIR2DL5.1
• Gene ID: 554278
• MIM: 605305
• UniProt ID: Q8N109
• Chromosome Location: 19q13.4