Active Recombinant Human EPGN Protein

• Cat.No.: EPGN-022H
• Product Overview: The mature recombinant human EPGN protein containing 51aa (L54-A104) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 54-104 a.a.
• Description: The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants.
• Bio-activity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells.
  The ED50 for this effect is 100-500 ng/mL.
• Molecular Mass: 6 kDa
• Product-Related Proteins: 54-104
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: EPGN epithelial mitogen [ Homo sapiens (human) ]
• Official Symbol: EPGN
• Synonyms: EPGN; epithelial mitogen; EPG; PRO9904; ALGV3072; epigen; epithelial mitogen homolog
• Gene ID: 255324
• mRNA Refseq: NM_001270993
• Protein Refseq: NP_001257922
• MIM: 618717
• UniProt ID: Q6UW88