Active Recombinant Human EDA2R, Fc-tagged, Biotinylated

• Cat.No.: EDA2R-600H
• Product Overview: The recombinant human EDA2R-Fc fusion is expressed as a 366 amino acid protein consisting of Asp2 - Thr138 region of EDA2R (UniProt accession #Q9HAV5) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: 2-138 a.a.
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Binds to its ligand EDA--A2 and blocks EDA-A2-mediated signaling activity.
• Molecular Mass: Calculated molecular mass (kDa): 40.9; Estimated by SDS-PAGE under reducing condition (kDa): 50-55
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: EDA2R ectodysplasin A2 receptor [ Homo sapiens ]
• Official Symbol: EDA2R
• Synonyms: EDA2R; ectodysplasin A2 receptor; tumor necrosis factor receptor superfamily member 27; EDA A2R; EDAA2R; TNFRSF27; XEDAR; EDA-A2 receptor; X-linked ectodysplasin-A2 receptor; tumor necrosis factor receptor superfamily member XEDAR; EDA-A2R
• Gene ID: 60401
• mRNA Refseq: NM_001199687
• Protein Refseq: NP_001186616
• MIM: 300276
• UniProt ID: Q9HAV5
• Chromosome Location: Xq11.1
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity; tumor necrosis factor-activated receptor activity