Active Recombinant Chicken IFNA

• Cat.No.: IFNA-1127C
• Product Overview: Recombinant Chicken IFNA was expressed in E.coli .

Specification

• Species: Chicken
• Source: E.coli
• Tag: Non
• Description: Chicken interferon alpha (IFN alpha) shares structural and biological properties with mammalian IFN1. Recombinant chicken IFN alpha (rChIFNa) has been shown to act as a highly potent anti-viral agent in vitro. rChIFNa also resulted in a noticeable delay in the progression of tumours in CC progressor chickens infected with Rous Sarcoma Virus, when admimistered intravenously. PAP004 is the immunogen used to produce the AbD Serotec chicken IFN alpha antibody.
• Molecular Mass: 19kD
• Purity: >85% by Ni chelate chromatography
• Activity: 1x107units/mg
• BufferSolution: 0.05M Sodium Acetate; 1M Sodium Chloride; 2M Urea; 10mM Beta-Mercaptoethanol
• Storage: Store at -20oC only. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
• Shelf Life: 3 months from date of despatch.
• OfficialSymbol: IFNA3
• Publications:
  Interferon Alpha Induces Multiple Cellular Proteins That Coordinately Suppress Hepadnaviral Covalently Closed Circular DNA Transcription (2020)

Gene Information

• Gene Name: IFNA3 interferon [ Gallus gallus ]
• Synonyms: IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma; interferon type A1/A2; IFN alpha; interferon alpha; interferon type A3
• Gene ID: 396398
• mRNA Refseq: NM_205427
• Protein Refseq: NP_990758
• UniProt ID: P42165
• Chromosome Location: Z
• Pathway: Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Herpes simplex infection
• Function: cytokine activity; cytokine receptor binding