Active Native Human CTSG protein

• Cat.No.: CTSG-1649H
• Product Overview: Native Human CTSG was purified from Human Neutrophil.

Specification

• Description: This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
• Source: Human Neutrophil
• Species: Human
• Form: Salt-free lyophilized solid.
• Bio-activity: 2-4 units per mg protein
• Molecular Mass: 23500
• Purity: >=95% by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme that hydrolyzes one umole of Suc-Ala-Ala Pro-Phe-pNA (1 mM) per minute at 25 centigrade in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
• Storage: Stored at -20 centigrade
• Tag: Non

Gene Information

• Gene Name: CTSG cathepsin G [ Homo sapiens ]
• Official Symbol: CTSG
• Synonyms: CTSG; cathepsin G; CG; CATG; MGC23078
• Gene ID: 1511
• mRNA Refseq: NM_001911
• Protein Refseq: NP_001902
• MIM: 116830
• UniProt ID: P08311
• Chromosome Location: 14q12
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Activation of Matrix Metalloproteinases, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem
• Function: heparin binding; peptidase activity; serine-type endopeptidase activity