VIM
-
Official Full Name
vimentin -
Overview
Vimentin is 57 kDa intermediate filament proteins in mesenchymal cells. It is attached to the nucleus, endoplasmic reticulum and mitochondria either laterally or terminally. Vimentin is important in the differential diagnosis of undifferentiated neoplasm. -
Synonyms
VIM;vimentin;HEL113;CTRCT30;epididymis luminal protein 113;FLJ36605
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- Rat
- Chicken
- Zebrafish
- Bovine
- E.coli
- Mammalian Cell
- Insect Cell
- Human
- HEK293
- Insect Cells
- Mammalian cells
- Bovine Lens
- HEK293T
- Yeast
- His
- Non
- His&T7
- GST
- His&Fc&Avi
- C-His-Strep
- Flag
- Myc&DDK
- His&Myc
Involved Pathway
VIM involved in several pathways and played different roles in them. We selected most pathways VIM participated on our site, such as Epstein-Barr virus infection,MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Epstein-Barr virus infection | GTF2E1,PSMC5,EIF2AK4,TRAF1,PSMC2,NFKBIB,POLR3D,SNW1,HSPA1L,HLA-B |
MicroRNAs in cancer | MAPK1,TNC,TP53,MARCKS,ITGA5,ZEB2,HDAC4,SIRT1,IRS2,PIK3R2 |
Protein Function
VIM has several biochemical functions, for example, double-stranded RNA binding,glycoprotein binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VIM itself. We selected most functions VIM had, and list some proteins which have the same functions with VIM. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
glycoprotein binding | AZGP1,HSPA5,RASA1,SHB,SERPINA1E,B2M,DNAJC5,SDC1,BBC3,EDEM2 |
scaffold protein binding | MDM2,KCNA5,KCNQ1,DSP,SHANK3,NLGN4Y,MAP2K2,NLGN1,PARK7,NCK2 |
structural constituent of eye lens | MIP,CRYBB2,CRYBB1,BFSP1,CRYGN2,LIM2.5,BFSP2,CPOX,CRYBA1,CRYGS |
protein C-terminus binding | HSPB7,VAMP2,SREBF2,ECM1,COIL,SNF8,HOMER3,KCNJ11,PHB2,PQBP1 |
protein binding | WDR4,BTN2A2,SENP1,EN1,TPI1,SFMBT1,CD247,HMG20B,FGF3,ZNHIT6 |
double-stranded RNA binding | EIF2AK2,YRDC,EIF2C3,DHX58,DGCR8,TUBA1B,OASL,TFRC,MBNL1,OASL2 |
structural constituent of cytoskeleton | TUBA8,TUBA3C,HIP1,TUBAL3,TUBB4A,CYLC1,ACTR3,TUBGCP3,TUBB,TUBB1 |
identical protein binding | DIAPH1,TARDBP,TNK2,MAP3K11,SERPINA1E,RPE,APLP1,NEFL,ECI1,BRI3 |
keratin filament binding | SIRT1,KRT14 |
Interacting Protein
VIM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIM here. Most of them are supplied by our site. Hope this information will be useful for your research of VIM.
KAT7;NOD2;AKT1
Resources
Research Area
Myogenesis MarkersMesenchymal Stem Cell Markers
Mesenchymal Cells and EMT
Neural Stem Cell Markers
Glial Lineage Markers
Neural Crest Cell Markers
Intermediate Filaments
Mesodermal Lineage Markers
Neural Progenitor Cell Markers
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References
- Fenoglio, C; Albicini, F; et al. Renal Fibrogenesis and Platinum Compounds in a Rat Model: A Novel Pt (II) Complex vs. Cisplatin. ANTICANCER RESEARCH 35:739-751(2015).
- Ripoll, VM; Lambrianides, A; et al. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. BLOOD 124:3808-3816(2014).