TXNRD1
-
Official Full Name
thioredoxin reductase 1 -
Overview
TRXR1 (thioredoxin reductase 1) is a selenocysteine-containing protein that is involved in redox homeostasis. Its canonical target is thioredoxin, another redox protein. Together, they are involved in many functions such as antioxidant regulation, cell pr -
Synonyms
TXNRD1;thioredoxin reductase 1;thioredoxin reductase 1, cytoplasmic;GRIM 12;Trxr1;TXNR;oxidoreductase;thioredoxin reductase TR1;thioredoxin reductase GRIM-12;KM-102-derived reductase-like factor;gene associated with retinoic and IFN-induced mort
Recombinant Proteins
- Rat
- Human
- Mouse
- Chicken
- Zebrafish
- Thauera selenatis
- C.elegans
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- Non
- GST
- His
- His&T7
- Myc&DDK
- His&Fc&Avi
Involved Pathway
TXNRD1 involved in several pathways and played different roles in them. We selected most pathways TXNRD1 participated on our site, such as Pyrimidine metabolism,Selenocompound metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with TXNRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Selenocompound metabolism | TRR1,TXNRD3,CCBL2,MARS,SPS2,SEPHS1,SCLY,PAPSS1,PAPSS2,MTR |
| Pyrimidine metabolism | PRIM1,NT5C2,POLR3E,NME7,PNPT1,CTPS2,ENTPD1,POLE,POLR2EB,POLR2E |
Protein Function
TXNRD1 has several biochemical functions, for example, electron carrier activity,flavin adenine dinucleotide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TXNRD1 itself. We selected most functions TXNRD1 had, and list some proteins which have the same functions with TXNRD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| thioredoxin-disulfide reductase activity | TRR1,NXN,TXNRD2,TXNRD3 |
| protein disulfide oxidoreductase activity | GRX2,GFER,TXN2,ERO1LB,TXN,GSTK1,GLRX5,TXNRD3,SH3BGRL3,PTGES2 |
| electron carrier activity | GRX2,NCF2,ACADSB,ACOX2,ADH5,NDUFA12,ACADS,AOX3,COX7A2A,PRKRA |
| protein binding | DPYSL4,ZBTB5,C14orf169,FCGR1A,SLC9A3,DYNLRB1,TH1L,ADI1,GLE1,CTNND1 |
| flavin adenine dinucleotide binding | MTO1,FOXRED2,ACAD9,FMO1,SQLEA,PPOX,AOX3,MTRR,IVD,MTHFR |
Interacting Protein
TXNRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TXNRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TXNRD1.
CAV1;Cav1;fhuB;DMRTC2;PPP1R16A
Resources
Related Services
Related Products
References
