Lcn2
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Official Full Name
lipocalin 2 -
Synonyms
LCN2;lipocalin 2;24p3;MSFI;NGAL;neutrophil gelatinase-associated lipocalin;p25;lipocalin-2;oncogene 24p3;siderocalin LCN2;migration-stimulating factor inhibitor;25 kDa alpha-2-microglobulin-related subunit of MMP-9
Recombinant Proteins
- Human
- Mouse
- Rat
- Dog
- Pig
- Cynomolgus
- HEK293
- E.coli
- P.pastoris
- Mammalian Cell
- Insect Cells
- Human Cell
- Insect Cell
- HEK293 cells
- HEK293F
- C-His
- HEK293T
- Mammalian cells
- Baculovirus-Infected Sf9 Cells
- Human Neutrophil
- His
- GFP
- Non
- Fc
- Flag
- GST
- His&T7
- His&Fc&Avi
- Myc&DDK
Involved Pathway
Lcn2 involved in several pathways and played different roles in them. We selected most pathways Lcn2 participated on our site, such as Iron uptake and transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with Lcn2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | CLCN1A,AQP6,SLC6A2,LCN12,SLC5A6A,ATP1A1A.3,SLC46A1,SLC17A3,SLC3A2A,AQP9B |
| Iron uptake and transport | ABCG2D,SLC46A1,TFA,FTH1B,FTH1A,CP,TCIRG1,ATP6V1G3,FLVCR1,TFR1B |
Protein Function
Lcn2 has several biochemical functions, for example, iron ion binding,protease binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Lcn2 itself. We selected most functions Lcn2 had, and list some proteins which have the same functions with Lcn2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| small molecule binding | RBP4L,MUP3,PTGDSB,PTGDSA,APODA.2,PAEP,LCN5,AMBP,MUP20,LCN15 |
| iron ion binding | CYP3A4,CYP1D1,JHDM1D,CYP2K16,TH2,CYP2A7,LEPRE1,ALOX8,CYP4A11,CYP4Z1 |
| protein homodimerization activity | PAFAH1B1,MGLL,HHEX,CDSN,CAMK2A,RPE,CPOX,GPD1A,KLHL7,MAP3K11 |
| protease binding | INS1,DVL3,HSPA6,MBP,TNFRSF10A,CST3,CSTA,SERPINA5,STIM1,Cstb |
| transporter activity | ATP6V0E1,SLCO1F4,SLC2A15B,SLC2A1A,AP4M1,LCN15,SYPL2,CRABP2B,LCN9,PMP2 |
Interacting Protein
Lcn2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Lcn2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Lcn2.
Resources
Research Area
Renal MarkersMetalloproteases and Regulators
Complement Regulatory Proteins
Medulloblastoma Biomarkers
Related Services
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References
- Cheng, L; Xing, H; et al. Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 81:31-38(2015).
- Guo, P; You, JO; et al. Inhibiting Metastatic Breast Cancer Cell Migration via the Synergy of Targeted, pH-triggered siRNA Delivery and Chemokine Axis Blockade. MOLECULAR PHARMACEUTICS 11:755-765(2014).
