Recombinant Human LCN2 Protein, His-tagged

• Cat.No.: LCN2-1151H
• Product Overview: Recombinant Human LCN2 Protein (Gln21-Gly198) with His tag was expressed in 293F.

Specification

• Description: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
• Source: HEK293F
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 22.2 kDa; Accurate Molecular Mass: 27 kDa
• Protein length: Gln21-Gly198
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: LCN2 lipocalin 2 [ Homo sapiens (human) ]
• Official Symbol: LCN2
• Synonyms: LCN2; lipocalin 2; p25; 24p3; MSFI; NGAL; neutrophil gelatinase-associated lipocalin; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; migration-stimulating factor inhibitor; oncogene 24p3; siderocalin LCN2
• Gene ID: 3934
• mRNA Refseq: NM_005564
• Protein Refseq: NP_005555
• MIM: 600181
• UniProt ID: P80188