Recombinant Human LCN2 Protein, GST-tagged

• Cat.No.: LCN2-001H
• Product Overview: Recombinant Human LCN2 Protein (19-198 aa (full-length)) with GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
• Source: E. coli
• Species: Human
• Tag: GST
• Molecular Mass: 48.9kDa
• Protein length: 19-198
• Purity: >95% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB).
• Applications: ELISA, Western Blot, Antibody Production, Protein array
• Quality Control Test: 10% SDS-PAGE stained with Coomassie Blue (CB) immunoblotting with anti-GST (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry.
• Storage: Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade.
• Expiry: All components are stable for 1 year of receipt, if stored properly.
• Storage Buffer: Lyophilized from a solution containing phosphate buffered saline (PBS), pH 7.4. No preservatives added.
• Shipping: Lyophilized at Ambient temperature

Gene Information

• Gene Name: LCN2 lipocalin 2 [ Homo sapiens (human) ]
• Official Symbol: LCN2
• Synonyms: LCN2; lipocalin 2; p25; 24p3; MSFI; NGAL; neutrophil gelatinase-associated lipocalin; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; migration-stimulating factor inhibitor; oncogene 24p3; siderocalin LCN2
• Gene ID: 3934
• mRNA Refseq: NM_005564
• Protein Refseq: NP_005555
• MIM: 600181
• UniProt ID: P80188