UBE2L3
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Official Full Name
ubiquitin-conjugating enzyme E2L 3 -
Overview
Protein ubiquitination requires the concerted action of the E1, E2, and E3 ubiquitin-conjugating enzymes. Ubiquitin is first activated through ATP-dependent formation of a thiol ester with ubiquitin-activating enzyme E1. The activated ubiquitin is then tr -
Synonyms
UBE2L3;ubiquitin-conjugating enzyme E2L 3;ubiquitin-conjugating enzyme E2 L3;UBCH7;ubiquitin-protein ligase L3;ubiquitin carrier protein L3;ubiquitin-conjugating enzyme E2-F1;ubiquitin-conjugating enzyme UBCH7;E2-F1;L-UBC;UbcM4
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- Human
- HEK293
- Mouse
- Insect Cell
- Wheat Germ
- E. coli
- Mammalian cells
- HEK293T
- GST
- Non
- His
- His&Strep
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
UBE2L3 involved in several pathways and played different roles in them. We selected most pathways UBE2L3 participated on our site, such as Ubiquitin mediated proteolysis,Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | ERCC8,UBA6,UBE2D4,KLHL13,BIRC2,UBE2E3,UBE2G2,RHOBTB1,SOCS1A,BIRC7 |
| Parkinsons disease | NDUFS3,PPIF,NDUFA13,SLC25A5,NDUFA9,UCHL1,UQCR11,NDUFC1,PINK1,NDUFA10 |
Protein Function
UBE2L3 has several biochemical functions, for example, ATP binding,enzyme binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2L3 itself. We selected most functions UBE2L3 had, and list some proteins which have the same functions with UBE2L3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | NME2,IKBKB,ATP2A2,KATNAL1,IKBKE,RFC5,RLN1,DYRK3,PDGFRB,DDX39 |
| protein binding | MKI67,LOXL3,ABCD2,CALU,FAM86C,THSD4,TAF1A,GOLSYN,ZNF16,TRIM26 |
| enzyme binding | BCL10,GSTM7,UBE2I,PUS7,FAM84B,MAPK8,HLCS,MAPK14,BRCA1,ATP2A2 |
| ubiquitin protein ligase binding | USP13,TRAF3,GPI1,MID1,MAGEA2,NEDD8,FZD6,PRKAR2B,UBE2KB,SMAD5 |
| poly(A) RNA binding | PRR3,SCG3,CCT6A,SLC16A3,HSPA8,LARP2,HNRNPU,HIST1H4D,RPS19,ANXA11 |
| ubiquitin conjugating enzyme activity | UBE2S,UBE2O,UBE2D1,UBE2J2,UBE2E1,UBE2V1,UBE2B,UBE2D3,UBE2D2,UBE2Q1 |
| ubiquitin-protein transferase activity | NSMCE1,UBA7,BRCA1,WWP1,RNF13,ANKIB1A,TRAF7,PARK2,RNF220,MARCH4 |
| transcription coactivator activity | VGLL2,PER2,PRPF6,TAF10,SP100,CREBBP,NR2F1,TAF9,PRDM16,CCNE1 |
| ubiquitin-protein transferase activator activity | AUP1,FBXW7,CBX8,RING1 |
Interacting Protein
UBE2L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2L3.
ARIH2;ospG;RNF19B;RNF125;CCNB1IP1;PARK2;CBL;UBE3A
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