Recombinant Human UBE2L3
Cat.No. : | UBE2L3-31661TH |
Product Overview : | Recombinant full length Human Ube2L3 is a single, non-glycosylated polypeptide chain containing 154 amino acids. Molecular mass 18 kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. |
Tissue specificity : | Ubiquitous, with highest expression in testis. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 50mM HEPES, 150mM Sodium chloride, 1mM DTT, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD |
Sequence Similarities : | Belongs to the ubiquitin-conjugating enzyme family. |
Full Length : | Full L. |
Gene Name | UBE2L3 ubiquitin-conjugating enzyme E2L 3 [ Homo sapiens ] |
Official Symbol | UBE2L3 |
Synonyms | UBE2L3; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme E2 L3; UBCH7; |
Gene ID | 7332 |
mRNA Refseq | NM_003347 |
Protein Refseq | NP_003338 |
MIM | 603721 |
Uniprot ID | P68036 |
Chromosome Location | 22q11.2 |
Pathway | Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; |
Function | ATP binding; acid-amino acid ligase activity; enzyme binding; ligase activity; nucleotide binding; |
◆ Recombinant Proteins | ||
UBE2L3-5064R | Recombinant Rhesus monkey UBE2L3 Protein, His-tagged | +Inquiry |
UBE2L3-17723M | Recombinant Mouse UBE2L3 Protein | +Inquiry |
UBE2L3-2296H | Recombinant Human UBE2L3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2L3-31661TH | Recombinant Human UBE2L3 | +Inquiry |
UBE2L3-33H | Recombinant Full Length Human Ubiquitin-conjugating Enzyme E2L 3/UBE2L3 Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
UBE2L3-570HCL | Recombinant Human UBE2L3 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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