IL36A
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Official Full Name
interleukin 36, alpha -
Overview
IL1F6 is a member of the interleukin 1 cytokine family. It has a conserved 12-stranded beta-trefoil structure. Binding analysis failed to detect interaction with multiple IL1R family members. IL-1F6 is a secreted cytokine that expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. -
Synonyms
IL36A;interleukin 36, alpha;IL1F6, interleukin 1 family, member 6 (epsilon);interleukin-36 alpha;FIL1;FIL1E;IL 1F6;IL1(EPSILON);MGC129552;MGC129553;FIL1(EPSILON);IL 1H1;IL1RP2;MGC151479;MGC151481;OTTMUSP00000012798;FIL1 epsilon;IL 1 epsilon;IL-1 epsilon;IL-1F6;IL1E;IL1F6;IL1F6_HUMAN;Interleukin 1 epsilon;Interleukin 1 family member 6 (epsilon);Interleukin 1 family member 6;Interleukin 36 alpha;Interleukin-1 epsilon;Interleukin-1 family member 6;RP23-176J12.4;OTTHUMP00000203688;IL-1F6 (FIL-1-epsilon);interleukin 1, epsilon;interleukin 1 family, member 6 (epsilon)
Recombinant Proteins
- Mouse
- Human
- E.coli
- Human
- HEK293
- Human Cells
- Non
- His
- DDK&Myc
- GST
Involved Pathway
IL36A involved in several pathways and played different roles in them. We selected most pathways IL36A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL36A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
IL36A has several biochemical functions, for example, cytokine activity,interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL36A itself. We selected most functions IL36A had, and list some proteins which have the same functions with IL36A. You can find most of the proteins on our site.
Function | Related Protein |
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interleukin-1 receptor binding | IL36B,TLR9,IL1A,IL1F10,IRAK1,TRIP6,IL1B,IL37,IL36G,IRAK4 |
cytokine activity | CSF1,Il1f9,IFNA4,GPI1,ADIPOQ,INHA,IL23,HMGB1B,VEGFA,EDN1 |
Interacting Protein
IL36A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL36A here. Most of them are supplied by our site. Hope this information will be useful for your research of IL36A.
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References
- Chen, DY; Chen, YM; et al. Th17-Related Cytokines in Systemic Lupus Erythematosus Patients with Dilated Cardiomyopathies: A Possible Linkage to Parvovirus B19 Infection. PLOS ONE 9:-(2014).
- Castro, M; Wenzel, SE; et al. Benralizumab, an anti-interleukin 5 receptor alpha monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study. LANCET RESPIRATORY MEDICINE 2:879-890(2014).