Il19
-
Official Full Name
interleukin 19 -
Overview
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. -
Synonyms
IL19;interleukin 19;interleukin-19;IL 10C;IL 19;MDA1;melanoma differentiation associated protein like protein;NG.1;ZMDA1;OTTHUMP00000034568;OTTHUMP00000216804;melanoma differentiation associated protein-like protein;melanoma differentiation-associated protein-like protein;IL-10C
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- Yeast
- Insect Cells
- HEK293
- CHO
- Human Cells
- His
- Non
- DDK&Myc
- Avi&Fc&His
Involved Pathway
Il19 involved in several pathways and played different roles in them. We selected most pathways Il19 participated on our site, such as Cytokine-cytokine receptor interaction,Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Jak-STAT signaling pathway | MTOR,PIK3R3A,IL11RA,PIM1,STAM,PIK3CG,STAT1A,IFNG1-2,IL24,PTPN6 |
| Cytokine-cytokine receptor interaction | IL7,CXCL12,CXCL14,IFNL3,TGFBR1B,PDGFAA,CCR6,IFNA21,CXCR4,CXCL3 |
Protein Function
Il19 has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Il19 itself. We selected most functions Il19 had, and list some proteins which have the same functions with Il19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IL5,IFNA16,GDF3,TNFB,IFNG,NRG1,BMP8B,SP100,IFNA7,BMP5 |
Interacting Protein
Il19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il19 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il19.
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